A bit of a rarity these days, Kanata no Astra happens to be a completed adaptation of a completed work. And though not quite a mixed genre series (the comedy is absolutely the main focus) it treats its dramatic aspects with all due seriousness without cutting any corners or using any cheap tricks. Really the only thing negative I can say about it is that there’s one plot twist too many; the overarching reasoning behind why they found a ship where they did ends up on just the wrong side of unbelievable… particularly when combined with the habitability of the various planets they visit.
The pseudo-gag comedy Watashi, Nouryoku wa Heikinchi de tte Itta yo ne! is unfortunately far less well structured. It combines 4th-wall breaking parody, 4th-wall breaking exposition, reaction humor, ecchi humor, serious drama, not-so-serious drama, action of both the sincere and not-so-sincere variety, and (at the very end) battle shounen elements. It is, simply put, a mess. They needed to either drop the dramatic/sincere bits or drop the nanomachine-related commentary and 4th-wall breaks, as the two do not mix well at all. Hell, even just sticking to one or two varieties of comedy might have resulted in something less scattershot.
Kanata no Astra:
Heikinchi:
