A couple years have passed since Sasuke left the village. Naruto and Sakura continue their search for him while Akatsuki persist on their quest to collect all of the Tailed Beasts, and all eventually get caught up in a catastrophe of world-ending scale.
Continuing from where the first series left off, this one ultimately isn’t much different besides having a fondness for flashbacks: It’s still a mix of comedy, action, and drama peppered with Anime-original filler content to extend the duration. The characters do behave less childishly though, and most of the canon content leans more toward the dramatic.
More Information:
aniDB
Crunchyroll
Wikipedia